Sentence examples for molecular subsets of from inspiring English sources

Different treatments may work in different molecular subsets of cancer, depending on the mutation.

This review traces the evolution of precision therapy for lung cancer from the identification of molecular subsets of the disease to the development and approval of tyrosine kinase, as well as immune checkpoint inhibitors for lung cancer therapy.

Although CRC is one of the best described cancers in terms of genetic and epigenetic events involved [2] [5], little is known about how measures of anthropometry and physical activity are associated with different molecular subsets of this disease.

In order to develop specific therapies based upon the genetic makeup of individual NSCLC tumors, we (the Lung Cancer Oncogenome Group at Memorial Sloan-Kettering Cancer Center (MSKCC)) and others have sought to define clinically relevant molecular subsets of lung cancer.

We identified robust molecular subsets of SSc esophageal disease that are distinct from clinically determined subtypes.

Much larger studies will be needed to address the predictive value of PIK3CA mutations in different molecular subsets of breast cancer in the context of different chemotherapies.

Ideally, an MGP would be developed for each molecular subset of breast cancer.

The EML4 ALK fusion gene defines a new molecular subset of NSCLCs with distinct clinical and pathologic features.

Therefore, an accurate and practical assay is urgently needed to detect this molecular subset of lung cancer [ 9].

In previous studies, ALK rearrangement represented a unique molecular subset of NSCLC with no overlap with cancers that featured alterations in the EGFR or KRAS genes [ 18, 19].

The study was particularly informative as very few of the patient groups had received systemic treatment, which is likely to benefit a molecular subset of patients and thereby modify the outcome.