Sentence examples for cellular subsets of from inspiring English sources

Over the course of the last decade, there has been a remarkable shift in research carried out in the heterogeneous field of neuro-oncology, which appears to be away from clinical descriptive studies, and toward more basic and fundamental investigation of the pathology, immunohis­ tochemistry, biochemical and cellular subsets of brain tumors.

The potential influence of differences in the cellular subsets of healthy vs. HIV infected individuals seems limited here as the total amount of CD14+ monocytes does not differ appreciably between the two patient groups, although the percentage of CD14+CD16+ monocytes is larger after HIV-1 infection.

In HCC numerous regulatory mechanisms involving nearly all cellular subsets of the immune system contribute to tumor development and progression.

In order to assess whether the markers chosen actually detect different cellular subsets of macrophages, tissue sections from five patients were initially stained for CD68, CD163, or HLA-DR, alone or in combination.

We previously examined the expression of mRNAs between cellular subsets of the developing mammary gland, found GATA-3 to be specifically expressed in epithelial cells and went on to identify GATA-3 as an important breast tumour suppressor gene [ 27, 28].

Treg cells are defined as a separate cellular subset on the basis of their surface phenotype as well as functional characteristics.

However, the precise mechanisms associated with the synergistic effects observed in the present studies were not fully characterized, and mechanistic studies will be required to identify the role of different cellular subsets in the generation of effective antitumor immunity.

This system allows automated quantitation of fluorescent staining on a per-cell basis and selection of cellular subsets (nucleus versus cytoplasmic) for analysis of target signals.

In support of this idea, we demonstrate that co-culture of complementary cellular subsets greatly influences the repopulation activity of their counterparts.

Analysis of the nature and function of cellular subsets associated with IA and immune regulation would assist in understanding HIV immunopathogenesis and developing strategies to target disease progression.

As accumulating evidence suggests that intratumor heterogeneity is a consequence of cellular subsets with different cycling frequencies, we developed a method for transcriptional profiling of gliomas, using a novel technique to dissect the tumors into two fundamental cellular subsets, namely, the proliferating and non-proliferating cell fractions.