Sentence examples for molecular function prediction from inspiring English sources

Seven groups were based on molecular function prediction by using the FunCat annotation scheme [ 21] and the predicted molecular function as guidance.

It is even a greater challenge to extend a molecular function prediction into a biological process prediction.

At the end, a set of sequentially similar sequence segments without any trustworthy molecular function prediction remains.

While the molecular function prediction of most of them clearly suggests an intracellular molecular function, in some cases the classifier also showed an ambiguous behaviour in separating SP and SA predictions.

The full list and functional annotation of thus identified proteins and the conditions under which they were detected are shown in Additional File 3. The genome of A. niger CBS 513.88 has been subject of an extensive molecular function prediction, followed by thorough manual verification.

Unfortunately, it emerged that this metric led to many methods (including BLAST) being outperformed by a naïve ranking of functions by prevalence (e.g. simply predict functions which are common overall; this approach ranks third or fourth in molecular function prediction), leading the organizers to exclude some results.

In an evaluation of the CSIDOP method we use protein-protein interaction data from the Homo sapiens genome, and find that CSIDOP is capable of making molecular function predictions for human proteins with accuracy of 95.42% using 2,972 gene ontology (GO) functional categories (the most specific terms in GO).

Further, while in vertebrates experimental data corroborate SMO and APAO molecular function predictions, in invertebrates the finding of a supported phylogenetic clusters of insect PAOs and the co-occurrence of two PAO variants in the amphioxus urgently claim the need for future structure-function studies.

Therefore, we hypothesized that by restricting minimotif predictions to those where the minimotif containing protein and target protein have a related cellular or molecular function, the prediction is more likely to be accurate.

Motifs may not be simple biological circuits [ 21], but they established the idea that local structure is important; one way in which this was later exploited was to compute node signatures for use in function prediction in molecular networks [ 56] and alignment of molecular networks [ 69].

Then, we discuss the relevance of the structure predictions for their predicted molecular function.