Sentence examples for molecular function analysis from inspiring English sources
GO molecular function analysis was performed by using the GOToolBox [21].
GO Molecular Function analysis showed that cell-to-cell signaling and interaction, metabolism and energy pathways were altered, consistent with the observation that diabetes is closely associated with metabolic dysregulation [29].
Table S3: Overrepresented GO terms for molecular function analysis of chromosome III.
Supplementary Table S3 Molecular function analysis of proteins with exclusive or up-regulated expression in preeclamptic umbilical cord blood plasma.
In addition, molecular function analysis showed that AHSG, C3 and HRG play a role in endopeptidase and peptidase inhibitor activity.
Supplementary Table S5 Molecular function analysis of proteins with absent or down-regulated expression in preeclamptic umbilical cord blood plasma.
The functional classification includes Gene Ontology (GO, including biological processes, cellular components, and molecular functions) analysis and physiological pathways enrichment analysis based on the KEGG (http://www.genome.jp/kegg/) and BioCarta (http://www.biocarta.com/) databases.
Pre-processing and quantile normalization of microarray data was performed with the AFFY57 package in R. From normalized RNA intensities, unbiased, differential expression analysis and a short list of genes (FDR < 0.05) was generated with the LIMMA58 package in R. Using the differentially expressed genes, pathway and molecular function enrichment analysis was performed in MetaCore GeneGo35.
Figure 3 shows this GO molecular function enrichment analysis.
Consistent with the molecular function GO analysis, 36.56% and 47.88% of Melampsora secreted proteins with a GO assignment were involved in binding (GO 0005488) and catalytic activity (GO 0003824), respectively.
Each response group was mapped to its molecular function; this analysis indicated that the Early group encodes cytokines or negative regulators of the IKK-NF-κB pathway, and the Late group encodes cell surface receptors, adhesion molecules and signal adapters.
