Sentence examples for modulation by phosphorylation from inspiring English sources

This enhanced flexibility and its modulation by phosphorylation might explain some of the functional antagonism between the closely related homologs FKBP51 and FKBP52.

Among them, troponin and tropomyosin confer not only Ca2+ sensitivity to contraction, but also modulation by phosphorylation of troponin I (cTnI) [ 4].

In seven diagnostic AML samples, a subset of leukemic blast cells that responded to SCF modulation by phosphorylation of p-Akt and p-S6 were observed (Table 2, Supplementary Table S1).

At a first glance, the view of eisosomes as stable, uniformly sized entities is at odds with the assembly-disassembly of Pil1 upon phosphorylation reported here, as we show that the assembly and organizational properties of eisosomes are subject to modulation by phosphorylation.

In addition, this proteomic analysis confirms the modulation by phosphorylation of the PEPCase in the leaves, suggesting that nitrogen availability could affect the circadian rhythms, as well as it shows that the form of this enzyme operating in roots could be modulated by monoubiquitination.

Here we shall review current knowledge regarding the modulation of STIM1 by phosphorylation.

In response to growth factors, hormones and amino acids, mTORC1 is classically known to regulate cell growth and proliferation through modulation of protein synthesis by phosphorylation toward its downstream effectors, S6K1 [8] and 4E-BP1 [1].

Modulation of protein stability by phosphorylation is becoming a common theme in biology, and examples of crosstalk between phosphorylation and ubiquitin-mediated degradation of proteins are increasingly being reported (Hunter, 2007).

These data suggest that the change in function of SERCAs is possibly mediated by a decline in their modulation by mechanisms such as phosphorylation, as opposed to a decline in protein levels per se.

This is due at least in part to the modulation of the TFIIB-CstF-64 interaction by phosphorylation of TFIIB serine 65.

This mechanism is initiated when growth factors bind to and activate their membrane receptor, resulting in activation of a phosphorylation cascade, culminating in modulation of nuclear receptor activity, most likely by phosphorylation of the nuclear receptor protein.