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The specific modulation by capsaicin may be valid for both the endothelial NOS and the nNOS.
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Neuendorf A, Hagenacker T, Büsselberg D. Differential modulation of voltage gated channels by capsaicin.
These results establish a pivotal role of mitochondrial dynamics during axonal ovoid formation and degeneration, and provide evidence that modulation of mitochondrial dynamics can reduce axonal degeneration caused by capsaicin.
This suggests that the permeability enhancement by compound 2 is reversible similarly to that by capsaicin.
Both the cofilin activation and occludin decrease contributed to the TJ opening by capsaicin.
Figure 1D shows the cumulative transports induced by capsaicin and latrunculin A (LatA).
Subjects judged the pain induced by capsaicin through a 0 100 point visuoanalogic scale (VAS) during application of capsaicin every 10 min for 60 min (till capsaicin removal).
A specific NK(2) receptor antagonist inhibited constriction caused by endogenous tachykinins released by capsaicin.
The recently cloned rat vanilloid receptor, VR1, can be activated by capsaicin, acid, and heat.
The ERK activation produced by capsaicin is totally suppressed by inhibition of either protein kinase A (PKA) or PKC.
Concentration-dependent CGRP release by capsaicin had an EC50 of 88 ± 5 nM (Figure 2).
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