Sentence examples for modification by phosphorylation from inspiring English sources
After post-translational modification by phosphorylation, KID undergoes a transition from disordered to well folded protein upon binding to KIX.
In addition, protein modification by phosphorylation represents a very rapid mechanism to regulate the binding capacity of tau.
Thus, post-transcriptional modification by phosphorylation appears to play a significant role in increasing the level of SIRT1 protein in cycling cells.
Recently it was discovered that YopJ is an acetyltransferase that inhibits the activation of these kinases by modifying serine and/or threonine residues in the activation loop thereby preventing their modification by phosphorylation [9], [10].
The "p" in the "sequence" column represents the modification by phosphorylation.
A few recent papers have drawn the attention to HDAC6 modification by phosphorylation.
These peptides contained seven novel modifications by phosphorylation, acetylation, ubiquitination and dimethylation (Table 4, Figure 3, Figure S2B).
Arrestin activities vary according to their own modifications by phosphorylation and ubiquitination, their interactions with dozens of other proteins [ 26], and the specifics of their interactions with receptors (e.g., low or high receptor-arrestin affinity can determine whether receptors are recycled or degraded [ 17]).
Secondly, receptor activity is controlled by posttranslational modification, namely by phosphorylation initiated by the interaction of growth factors such as the IGFs and epidermal growth factors (EGFs) with their cognate receptors and consequent signal transduction.
After FRQ is synthesized, it is subjected to progressive post-translational modifications by phosphorylations that lead to its degradation by the ubiquitin/proteasome pathway.
A plethora of studies have demonstrated that archaeal proteins are subject to post-translational modification by covalent phosphorylation, but little is known concerning the identities of the proteins affected, the impact on their functionality, the physiological roles of archaeal protein phosphorylation/dephosphorylation, and the protein kinases/phosphatases involved.
