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Work with TM helices in various model systems has revealed a small number of specific dimerization sequence motifs, and it has been suggested that RTK dimerization is modulated by such motifs.

These studies reported that first-order sequential effects were not modulated by such expectancies.

As FACT can be post-translationally modified, for example, by CK2 or PARP1 (Li et al, 2005; Heo et al, 2008), rRNA gene expression might also be rapidly modulated by such activities.

Such a notion implies similarly unrefined functions modulated by such a neurotransmitter system, such as "readiness for cognition", "gating of cortical information", or even less defined functions such as "arousal".

The activities of proteins such as the phosphatases PTP1B and PTEN, caspase-3, and STAT3 are well known to be modulated by such thiol redox switching between reduced and oxidized states [12].

In light of extensively shared regulatory mechanisms between NRs (Table 1), it is tempting to speculate that many more NRs may be modulated by such post-transcriptional/translational regulation machineries.

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Targeting the endothelial cell surface molecules modulated by hyperglycemia, such as caveolin-1 and ACE could be an additional therapeutic strategy in diabetes.

For a better understanding of eating behavior, it is necessary to determine how it is modulated by factors such as the calorie content of food, satiety and gender.

This in turn will allow in future studies the analytical quantification of the transmission of information among the elements of this recurrent network and of how information transmission is modulated by factors such as the strength and dynamics of external inputs.

GRSs are modulated by factors such as environmental stimuli [25], nutritional status of the animal [12], and other changes over the honeybee's life related to their behavior [18].

These findings provide further evidence that enhanced contact stability modulated by proteins such as NLG-1 potentiate the recruitment of presynaptic elements to sites of contact between dendritic filopodia and axons.

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