Sentence examples for modulated by oestrogen from inspiring English sources

The genes specifically modulated by oestrogen comprise members of all functional compartments and processes in the cell.

Docetaxel is a substrate for ABCB1 whose function has been shown to be modulated by oestrogen and progesterone.

Serum lipids, pro-inflammatory cytokines and the RANK system have been suggested as common pathogenic links modulated by oestrogen.

The role of G-protein-coupled receptor and epidermal growth factor (EGF) receptor in an ER-independent signalling pathway modulated by oestrogen was investigated.

On the other hand, they might, if indeed creatine kinase expression is modulated by oestrogen – and in particular, ubiquitous mitochondrial [uMt] CK - as has been suggested for placental creatine kinase [ 103].

Pancreatic cancer cells are ER alpha and beta positive and consequently may be modulated by oestrogen [ 101] which is consistent with similar mechanisms observed in xenoestrogen-related cancers [ 102, 103].

Significantly, in breast cancer cells, the presence of a functional ER has been shown to be necessary for expression of E-cadherin [ 18], thus suggesting that its expression and subsequent cell-cell adhesion, may be modulated by anti-oestrogens and may have a bearing on the invasive growth of tumours.

The data are modulated by 16QAM modulation.

Oxytocin and oestrogen receptor function is modulated by the amount of cholesterol in the uterine myometrial plasma membranes and extraction of cholesterol from myometrial plasma membranes in vivo has been demonstrated to greatly enhance spontaneous contractions [ 20].

Production of the sex hormone oestrogen can also be modulated by insulin and hyperinsulinaemia, and this is thought to play a role in tumorigenesis 2. Indeed, it has been postulated that several mechanisms may underlie the association between breast cancer and diabetes, including activation of the insulin pathway, activation of the IGF pathway and altered regulation of sex hormones 88.

Similarly, transcriptional activity of oestrogen receptor, ERα, is also modulated by p42/p44 MAPK pathway stimulation [ 27].