Sentence examples for modifying the enzyme from inspiring English sources

Reversible TG2 inhibitors block substrate access to the enzyme active site without covalently modifying the enzyme.

Irreversible inhibitors such as KCC009 or KCA075 prevent enzyme activity by covalently modifying the enzyme, thereby preventing substrate binding.

Modifying the enzyme does prevent LVX action; however it has been shown to have no effect on DNA binding, therefore maintaining a fully active gyrase [ 46].

We then characterise the resulting enzyme activity, analyse the pH-dependency of catalysis and use X-ray crystallography to investigate the structural basis of the changes brought about by modifying the enzyme.

These studies suggested that prolonged exposure to circulating enzyme, whether achieved by repeatedly infusing large doses, or by chemically modifying the enzyme to delay its clearance, enhanced the likelihood of neuronal correction.

Significant efforts have been made to "humanize" plant N-glycan structures, either by retaining the recombinant proteins in the endoplasmic reticulum (ER) [ 4] or by modifying the enzyme machinery in the Golgi apparatus to eliminate plant-specific β 1, 2 -xylose and α(1,3)-fucose residues [ 5] and extend plant N-glycans with terminal β(1, 4)-galactose residues [ 6].

So the company modifies the enzyme slightly, by inserting something called an intein into the enzyme.

Arginine and ADMA are substrate and inhibitor of endothelial nitric oxide synthase, respectively; thus the ratio of arginine to ADMA may modify the enzyme activity [ 30].

It may also affect cell reprogramming by modifying the lipogenic enzymes acetyl-Co A carboxylase and fatty acid synthase [ 89].

The products of the sirtuin genes work by regulating the expression of genes and modifying the activity of enzymes.

They modified the Cas9 enzyme itself to change the way it interacts with DNA.