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Transcriptional activation of a number of IFN-inducible genes was rapid and independent of new protein synthesis, indicating that IFNs activated transcription by modifying the activity of pre-existing proteins and transcription factors.
Modified versions of these surrogates should provide agents capable of modifying the activity of these targets and enable one to study their involvement in specific biological processes as a means of target validation for downstream drug discovery.
Thus, oncogenic activation can also interdict TGFβ growth inhibitory responses by modifying the activity of downstream elements such as cell cycle inhibitors or transcriptional cofactors of Smad transcription factor activity.
They made the surprising discovery that the virus was only the indirect cause; it triggered the cancer by modifying the activity of a gene already within the cells.
Simple measures such as icing, using nonsteroidal anti-inflammatory drugs (NSAIDs), and reducing or modifying the activity that aggravates the symptoms can be instituted early in treatment.
We showed 5-HT1B and 5-HT1D inmunoreactivity in SPG neurons, which suggests a role in modifying the activity in SPG.
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They participate in Ca2+ signal transduction by binding and modifying the activities of specific target proteins.
In addition, instructors may consider using or modifying the activities available from the BioQUEST Curriculum Consortium (2011) or resources from the National Institute of Mathematics and Biological Sciences (NIMBIOS; 2011).
Such understanding would be helpful for enhancing, re-directing or modifying the activities of T cells under physiological and pathophysiological circumstances.
To expand its engagement and learning potential, we modified the activity for small groups and incorporated several active learning elements.
Moreover, green tea catechins have the ability to modify the activity of multiple intracellular molecular targets, including mitogen-activated protein kinase (MAPK), protein kinase C, and PI3K/Akt pathways.
More suggestions(15)
modifying the organization
changing the activity
modifying the support
modifying the occupation
modifying the interest
adapting the activity
change the activity
changes the activity
modifying the algorithm
modifying the draff
modifying the car
modifying the proof
modifying the tradition
modifying the scheduling
modifying the character
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