Sentence examples for modifying the inhibitory from inspiring English sources
On the other hand, many other reported effects of estrogen in hippocampal area CA1 might confer increased sensitivity to ischemia, either by modulating the excitatory effects of glutamate or by modifying the inhibitory effects of GABA.
Because AMP and its metabolite, adenosine, were less inhibitory to rat T cell proliferation than was NAD or ADP-ribose, pyrophosphatases may serve a regulatory role in modifying the inhibitory effect of ecto-NAD on T cell activation.
The apparent binding conformations of all the compounds at the active site of falcipain - 2 and the hydrogen-bond interactions which could be used to modify the inhibitory activities are identified by using Surflex-dock study.
These compounds were designed as potential multisubstrate inhibitors of thymidine phosphorylase based on an assumption that the potential hydrophobic effect of the aryl groups might modify the inhibitory effect towards this enzyme and they may also demonstrate cytostatic activity.
It had been reported that propranolol could modify the inhibitory effect of U50488 in isolated right atria of rat [ 4, 7], and the κ-receptor agonist could inhibit norepinephrine release from cardiac sympathetic nerve [ 25].
Given that CSPGs are a major barrier to repair and regeneration, a key experimental strategy for enhancing axonal regeneration and plasticity has been to modify the inhibitory extracellular environment.
Therefore, we have examined whether overexpression of HER2/ neu (erbB2), a potent inducer of Ras/MAPK signaling, modifies the inhibitory effect of TGF-β against MCF-10A human breast epithelial cells.
We asked whether environmental stimulation promotes neuronal plasticity by modifying the expression of growth-inhibitory molecules, specifically those of the extracellular matrix.
Thus, oncogenic activation can also interdict TGFβ growth inhibitory responses by modifying the activity of downstream elements such as cell cycle inhibitors or transcriptional cofactors of Smad transcription factor activity.
The inhibitory effect of dexamethasone on active MMP-1, without modifying the ratio between active MMP-1 and total MMP-1 activity, rather suggests an increase in inhibitory molecules.
CTLA4 is one of several co-inhibitory molecules that aid in modifying the T-cell response to antigen activation.
