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Exact(6)
Lipid A modifications are regulated by the environmental sensor-kinase transcriptional regulatory system PhoP-PhoQ and catalysed by PagP, PagL and LpxO which lead to acylation, deacylation and hydroxylation of the molecule, respectively [12], [13], [14].
These modifications are regulated by histone acetyl transferases and histone deacetylases (HDAC).
As indicated by our study, many genes involved in the degradation of damaged protein and protein modifications are regulated by transcription factor gene RPN4.
In Salmonella, LPS modifications are regulated by the two component pathway PhoPQ [ 46] and deletion of phoP in Pl leads to a mutant that is both avirulent and also sensitive to the AMP polymyxin B [ 47].
Whereas the genome distribution of several histone modifications has been measured in many different cell types, how these modifications are regulated at the single cell level in vivo remains largely unknown.
Epigenetic changes are a hallmark of aging - but it is yet unclear how these modifications are regulated [ 6].
Similar(54)
Each of these reversible modifications is regulated by specific enzymes and has the capability of changing dynamically.
However, it remains largely unknown how this site-specific modification is regulated within the Golgi apparatus.
This fact together with previous findings about mammalian H1, suggest that this modification is regulated during mitosis.
We were interested in whether the modification is regulated by the activation status of Kss1 and what functional roles sumoylation of Tec1 may have in regulating signaling outcome of the Kss1-mediated invasive pathway.
It is also unclear how CRL4- and PCNA-dependent degradation of other targets is compatible with Y211 phosphorylation, or how this modification is regulated.
Related(20)
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adjustments are regulated
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