Sentence examples for models with defects from inspiring English sources

According to the damage criterion set reasonably, the damage evolution of the models with defects can be simulated.

The development of animal models with defects in RP genes will be essential for studying these questions.

Indeed, constitutively activated p53 is considered to be a pro-aging factor, contributing to premature aging phenotypes displayed in mouse models with defects in genome maintenance [27].

Mouse models with defects during zygotene include the Dmc1 (Yoshida et al., 1998) and the Dnmt3L knockout lines (Webster et al., 2005).

While these models, with defects in leptin physiology, develop severe steatosis, NASH does not occur unless animals are challenged with endotoxin [ 31] or fed a methionine/choline-deficient diet [ 32].

Mouse models with defects at the leptotene stage include: the platelet-activating factor acetylhydrolase 1b alpha 1 and alpha 2 double knockout mouse line (Yan et al., 2003), and the Msh5 (de Vries et al., 1999) and Spo11 knockout mouse lines (Romanienko and Camerini-Otero, 2000).

The wave propagation characteristics of the multi-layered model with defects are assessed with dynamic FEM analyses under three-dimensional conditions.

The paper is "an important milestone," says Laurent Segalat, a geneticist at the University of Lyon, France, because it finally links the worm muscular dystrophy model with defects in acetylcholine transport and breakdown.

In the eyes of Rdh8−/− Abca4−/− mice, a mouse model with defects in retinoid cycle that displays some symbolic characteristics of age-related macular degeneration (AMD), the level of atRAL-dimer was increased compared to wild-type mice, and was even much greater than that of A2E & isomers.

This dissociation of RNA/protein levels of globin genes was confirmed in another zebrafish DBA model with defects in rpl11.

There is evidence in both human ALS and in mouse models, that motor neurone death occurs by the type of 'dying back' axonal degenerative pathophysiology, that would be predicted in this model, with defects of neuromuscular transmission, end-plate denervation, and 'peripheral pruning' of axons as the earliest observed events [ 112- 114].