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This translates to minimal cell loss.
Since MSCs constitute a relatively rare subset of bone marrow cells, preparations for clinical purposes require a minimal cell loss during manufacturing steps including preservation of the cells.
The unique gelation properties of UCG enabled the encapsulation of cultured cells in CFM of high solid volume (>5%) and elasticity (1.28 ± 0.15 kPa at 5% and 4.82 ± 0.38 kPa at 8%) with minimal cell loss.
Proliferation also occurred, although to a lesser extent, in nutrient deprived cultures, yet associated with no or minimal cell loss.
This observation may be due to the incision wound having minimal cell loss, since in this situation a tissue injury can be closed within 6 12 h if not contaminated [ 1].
Similar(55)
After exposure of endothelialized valves to pulsatile flows for 24 hours (80 beats/min, 3.4 L/min), there were minimal cell losses from the bioprostheses.
Following a rest phase preconditioned cells were exposed to 24 h hypoxia, and demonstrated minimal overall cell loss, whilst controls (not preconditioned, but exposed to 24 h hypoxia) demonstrated a 44% cell loss.
However they have clinically mild retinal degeneration with minimal retinal cell loss (16, 19, 20, 55, 62, 69), unless present on a mixed CD1 albino background (60).
Preliminary experiments carried out using corneas held in MegaCell™MEM and transferred to the same medium containing 4 % PEG 10,000 indicated that this polymer would thin them with minimal endothelial cell loss over a 14 day period.
Critically, new avenues in neuroprosthetic fabrication have come on-line from a recent focus on novel biomaterials strategies to develop innovative biocompatible materials that mimic neural tissue characteristics, cause minimal inflammation and neuronal cell loss, and are chronically stable in vivo.
Thus, at 4 weeks post-infection, a time point at which mutant-Htt-induced cell loss is minimal in this model [11], we observed a clear cut increase in the number of small neuropil-like aggregates in older rats as compared to younger rats.
Related(20)
little cell loss
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minimal hearing loss
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minimal cell functioning
minimal cell elongation
minimal cell trauma
minimal cell division
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