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Economic growth is but a small benefit of migration when compared to the opportunity to grow through interactions with others of different backgrounds.
The microchannels enhanced 3D migration when compared to the flat samples, which made only 2D migration possible.
When resting endothelium was used, T cells which had been activated by crosslinking CD3 for only 1 min showed a significant reduction (p < 0.0001) in migration when compared with untreated T cells.
Eluates collected from electrospun scaffolds, which were loaded with 4 or 8 μg PDGF/mL polymer solutions, demonstrated similar levels of fibroblast migration when compared to a single 50 ng/mL treatment.
VSMCs cultured in monocyte/MDM-conditioned medium (MCM), generated from the culture of monocytes/MDM on D-PHI scaffolds for up to 28 days, similarly affected VSMC contractile marker expression, growth and three-dimensional migration when compared to direct VSMC monocyte co-culture.
In no case did scrambled siRNA have any effect on cellular migration when compared to untreated controls.
Similar(36)
MCF-10A cells inoculated on aligned fiber displayed no significant difference in total migration when comparing either control vs. vehicle or in the presence of a CXCL12 gradient.
FAK deficiency in ECs inhibited the speed of migration and persistence of cell migration significantly when compared with FAK+/+ controls (Fig 4A, p < 0.01).
Knockdown of MAP3K1 in MDA-MB-231 cells causes reduced migration towards serum growth factors in transwell migration assays when compared with MDA-MB-231 cells transfected with a control small interfering RNA.
In the transwell invasion and migration assay, cells transfected with miR-22 mimics displayed an inhibition in invasion and migration ability when compared with the control group in SGC-7901 cells.
In this assay, known inducers of endothelial migration such as FGF-2 and VEGF, promoted a >2 fold or 1.5 fold increase in endothelial migration, respectively, when compared to serum free media (DMEM) (Figure 6B).
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