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In addition to computer simulations, we also present experimental data of hybridization collected on our microarray system for different flow rates.
Here we describe a user-friendly microarray system for genome-wide analysis of gene expression in Tetrahymena.
By investigating more epitopes and shifting the targets from well-established Ag-specific T cell lines to highly heterogeneous clinical samples, our aim was to adapt, simplify and standardize this peptide:MHC cellular microarray system for translational studies.
A third mode of action was revealed using an oligonucleotide-based DNA microarray system for HSV.
To provide a useful, focused microarray system for RNA diagnostics, we developed a novel platform termed Genopal™, which is comprise a hollow fibre array (Fig. 1).
To screen large numbers of isolates in short time periods, we used a microarray system for high-throughput dot-blot hybridization [ 17].
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Because the functional molecules in cells are protein, proteome analysis based on 2-D gel electrophoresis is believed to have several advantages over cDNA/oligonucleotide microarray systems for clinical use.
Fortunately, recent advances in next generation sequencing technologies, coupled with the production of high-density microarray systems for highly multiplexed genotyping, have made genome-wide genotyping with thousands of single nucleotide polymorphism (SNP) markers possible [ 50], thus providing an efficient and cost-effective means of saturating genome maps.
A viable methodology for specific detection of any protein is demonstrated by the NANOSPAD microarray system, suitable for application in the rapidly growing field of proteomic research.
This study presents the kinetic, equilibrium, and thermodynamic analyses of DNA hybridization in a microarray system designed for fast molecular testing of pathogenic bacteria.
This overview recounts the background to the development of a microarray system that is poised for surveying proteomes for carbohydrate-binding activities and glycomes for assigning the oligosaccharide ligands.
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