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To establish a modified microarray method for detecting HBV gene mutations in the clinic.
Additional detailed descriptions of strain, sex, tissue preparation and microarray method for each individual database is available at www.genenetwork.org.org
Shabani et al. presented a phage-modified electrode microarray method for rapid and direct impedimetric detection of B. anthracis [ 88].
We have performed a large preclinical validation study to determine the accuracy of a new microarray method for molecular karyotyping.
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RNA-Seq technology has several advantages over DNA microarray methods for transcriptional analysis.
The development of microarray methods for large-scale analyses of mRNA gene expression has made it possible to search systematically for key molecules [ 30, 31].
Traditional microarray methods for uncovering prognostic expression signatures, based primarily on empirical associations not requiring plausible biological relevance of the markers used, are now sharing the stage with mechanistically motivated strategies driven by knowledge of oncogenic pathways and processes.
The Spearman correlation of the transcriptome across technologies is 0.61 (Additional file 3), which is consistent with several studies comparing RNA-seq and microarray methods for genome-wide transcriptome profiling [ 31- 33].
This method has advantages that the microarray method lacks, for example in the discoveries of novel and variant miRNAs.
Specific examples include miniaturized, automated, combinatorial material synthesis and extracellular matrix screening methods as well microarrayed methods for creating local microenvironments of soluble factors, such as small molecules, siRNA, and other signaling molecules.
A microarray method was developed for the detection of 40 bacterial species reported in the literature to be predominant in the human gastrointestinal tract.
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