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An expression microarray screen for targets of unliganded GR was performed using our GR-depleted cell lines maintained in the absence of glucocorticoids.
One notable exception is the 12-membered macrocycle robotnikinin, which was discovered through a small-molecule microarray screen for compounds that can bind recombinant Shh (34).
We previously performed a DNA microarray screen for OsIRE1-dependent genes using OsIRE1 knocked down rice plants in ER stress condition [ 6, 21].
The presence of midkines in the zebrafish retina was first discovered in a microarray screen for genes whose expression is induced by photoreceptor death and during photoreceptor regeneration (Calinescu et al., 2009a).
In a microarray screen for nuclear, polyadenylated noncoding RNAs, we identified three abundant transcripts with significant nuclear retention: the canonical ncRNA, XIST, and two large noncoding loci on human chromosome 11.
In our microarray screen for transcriptional effects of ERβ expression in ERα-positive cells, statistical analysis indicated a significant enrichment of genes from two cell growth-associated functional categories within the population of genes downregulated by ERβ in the presence of E2 (Tables 2 and 3).
Similar(54)
Microarray screens for upstream regulators of cVg1.
Small-molecule microarray screening for TFIID-specific modulators.
Here, we provide comparative staging of ray and disc flower development and microarray screening for differentially expressed genes, accomplished via microdissection of hundreds of coordinately developing flower primordia.
There is good agreement between the genes highlighted by our in-silico binding-site search and by microarray screens for downstream targets of hoxb1 in rhombomere 4 of zebrafish [ 52] and mouse [ 53].
Id2 was identified in DNA microarray screens for rhythmically expressed genes [3 5], and further analysis revealed a circadian pattern of expression of all four Id genes in multiple tissues including the suprachiasmatic nucleus.
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