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DNA microarray experiments provide expression levels of thousands of genes under different conditions.
Many microarray experiments provide expression values for a list of probes instead of genes.
Microarray experiments provide more information than what the authors can interpret alone.
While the limited knowledge of loop thermodynamics does not allow prediction of such binding, microarray experiments provide a rapid way to reveal them.
cDNA microarray experiments provide a snapshot in time of gene expression levels across potentially thousands of genes and several time steps [ 19].
For instance, microarray experiments provide powerful data sets containing a wealth of information about the expression of genes that can be exploited by statistical analysis methods in order to interrogate data systematically [ 8- 14].
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Additionally, the integration of 30 microarray experiments provides a prospective analysis for identifying phosphorylation-associated biomarkers in 39 cancers.
MWW conceived the study, coordinated microarray experiments, provided biological expertise and interpretation, and assisted in manuscript writing.
Our results underline the utility of the T7 based RNA amplification for use in microarray experiments provided that all samples under study are equally treated.
The widely used DNA microarray experiments, providing a transcriptome-wide measure of mRNA levels, are limited by the need to extrapolate from mRNA levels to protein and complex levels, bridging over post-transcriptional effects, which are, in large, still not sufficiently understood.
RWL conceived the study, carried out the microarray experiment, provided data analysis, and drafted the manuscript.
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