Microarray experiments have the potential to incur considerable costs, particularly when using commercial arrays or gene chips.
cDNA microarray experiments have indicated that E2F-1 is one of the genes whose expression was decreased by CREB silencing.
Microarray experiments have been extensively used to define signatures, which are sets of genes that can be considered markers of experimental conditions (typically diseases).
Microarray experiments have revealed that these three operons are regulated by erythritol in B. abortus, reinforcing that the three clusters participate in erythritol catabolism (Sangari et al, unpublished).
Several microarray experiments have been done to study the effect of hyperoxia using Drosophila as a model [30], [31], but the tissues analyzed and the length of hyperoxia exposure differed among these studies.
Recently, protein binding microarray experiments have shown that the sequence variety and position-interdependence between bases in sequence motifs are even higher than previously expected, and that TFs bind a rich spectrum of k-mers not fully captured even by multiple PWMs [7].
Microarray experiments have provided a systems-level view of the major effects of high fat (HF) diet within individual tissues, and have shown that HF diet often increases the expression of genes disproportionately associated with immune system processes, such as the processing and presentation of antigens [15], [21] [24].
Good DNA microarray experiments have clear objectives.
The SNP microarray experiments have been described previously [ 26].
Time-course microarray experiments have been widely used to identify cell cycle regulated genes.
Microarray experiments have been used to identify additional genes involved in nitrate/nitrite assimilation [ 61].
