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Using RhoH-deficient mice, the analysis of the function of RhoH in T-cells was investigated in more detail.
Obesity-related differentially expressed proteins (both MT and co-purified non-MT) were analyzed in pair-wise comparisons of non-fasted mice; the analysis was independent for each group of obese mice.
Overall, similar to our findings in CX3CR1GFP/+ mice, the analysis of microglial morphology based on IbaI expression in WT mice revealed a significant reduction in process formation and microglial volume coverage in old mice (Fig. S1).
Finally, in mice, the analysis of meiocytes from XX females, XY males, XY sex-reversed and XO females indicated that recombination patterns depend more on being a male or a female than on the true chromosomal genotype [ 43].
Pertinently, as in WB mice, the analysis of the distribution of anti-NPM and aCL antibodies in these SLE sera (Table 1) indicates that these autoantibodies were associated (χ2 = 9.2; P = 0.002).
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Importantly, DAT-KO mice continued to display lower peak HTO frequencies than WT mice when the analysis was restricted to periods when both groups were completely still (WT mice: 6.9±0.3 Hz, DAT-KO mice: 5.7±0.4 Hz; n = 5 per group).
For comparison of cellular and tissue parameters between the wild-type and mutant mice, the statistical analysis was performed using the Microsoft Excel data analysis program for Student's t-test analysis.
At 12 weeks of age blood samples were taken from fed mice for the analysis of 20 clinical chemical parameters (see Table S3).
Unfortunately, early lethality of Math6 null mice prevents the analysis of the function of this factor in pancreatic organogenesis; however, it does suggest that Math6 plays a role early in germ layer specification.
GS and SS provided the mice for the analysis.
Thus, making microinjection transgenic mice requires the analysis of multiple founder lines.
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