Besides mutant mice, the lab also maintains a computer database, Mouse Genome Informatics (www.informatics.jax.org), which assembles most known information about the mouse.
The cohousing also changed how the mice responded to new infections: After mingling with the dirty mice, the lab mice showed 10,000-fold increase in their immune response against a bacteria known as Listeria monocytogenes a reaction on par with pet store mice themselves.
Afterwards, they returned the mice to the lab, let ones within each group interbreed, and took some cells from the tails of both the mice and their offspring.
In some instances, the number of cancers exceeded the numbers ever seen in mice in the lab, the investigators said.
But the mice in the lab of Shigeru Watanabe, a psychologist at Keio University in Japan, have a more enjoyable life than most.
The last year, I took charge of all of the mice in the lab, around 300 cages.
Expanding your horizons could help expand your brain: German scientists found that mice in the lab who explored new environments grew more new neurons in the hippocampus, an area of the brain that supports learning and memory, than mice who were passive and adventure-resistant. 11.
The filtered supernatant was used to infect bone marrow cells from either wild type or MEKK1-deficient mice from the lab of Bing Su.
These results mirror experiments in mice in the lab of Meier-Abt and colleagues [ 13], who found that gene expression patterns altered most dramatically in the mammary stem cell population.
PI3KγKD/KD mice expressing the OT-II transgenic TCR were generated by cross-breeding OT-II transgenic mice (the Jackson Lab) with PI3KγKD/KD mice in C57BL/6J genetic background.
Due to the efforts involved in breeding and treating these mice, the replicating lab will approximate as closely as possible the same numbers of male and female mice used, based on the sexes they obtain in their breeding.
