Sentence examples for mice the knockout from inspiring English sources

Compared to control mice, the knockout animals spent significantly more time engaged in novelty-seeking behavior.

In these mice, the knockout of LAMP-2 leads to cardiomyopathy and an increase in the amount of autophagy/lysosome compartments in many tissues [30].

To test this hypothesis, carbohydrate expression at the cell surface of neurons isolated from L1+/y (wt) and L1−/y (ko) mice (the knockout of L1 is shown in Fig. S1) was assayed by flow cytometry.

Compared with wild-type mice, the knockout mice (mdr−/−) had a hippocampal drug concentration that was increased by 46% after the injection of phenobarbital.

In mice, the knockout of the Abl-related gene (Arg/Abl2) alone is well tolerated, but the combined loss of Abl and Arg caused early embryonic lethality.

So far, programs of the whole genome knockout mice, like the Knockout Mouse Project (KOMP) and the European Conditional Mouse Mutagenesis Program (EUCOMM), have generated thousands of conventional and conditional knockout mouse strains and are distributing them worldwide [ 154].

There was no difference in the number of leukocytes accumulating in the exudates of male vs female mice in either the knockout mice or wild-type mice.

However, unlike the knockout mice, Ku80 heterozygous mice grow to a normal adult size.

Moreover, the brains of the knockout mice resembled those of normal mice already "sensitized" to cocaine.

We are now investigating the role of C/EBPδ in the skeletal growth using the knockout mice as well as the double knockout mice of C/EBPβ and C/EBPδ.

The knockout mice lived only half as long as 30 normal mice did, the researchers found.