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T cells from p27 −/− Lck-Bcl-2 mice show delayed kinetics of CDK2 Thr-160 phosphorylation.

Hypothyroid wild type mice show delayed diastolic cardiac relaxation or delayed relaxation of papillary muscle.

Neonatal hUGT1 mice show delayed expression of hepatic UGT1A1 and are severely hyperbilirubinemic.

Moreover, Conde et al. also reported conflicting results using Parp1 –/– (deleting exon 4p53 /–/– mice, where the mice show delayed tumor formation, possibly due to abolition of nitric oxide synthase (iNOS) expression (Table 3).

Cx43 is present on radial glia fibers at the points where they contact with migrating neurons and Cx43 conditional knockout mice show delayed neuronal migration together with impairment in the lamination of the neocortex.

Nod1−/− and Nod2−/− mice show delayed pulmonary bacterial clearance and evidence of defective iNOS (inducible nitric oxide synthase) expression and NO (nitric oxide) production (as observed using macrophages in vitro), suggesting that C. pneumoniae is recognized by both of these intracellular receptors [ 72].

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Treated mice showed delayed onset of ataxic gait and tremor, significantly increased lifespan, and greatly reduced accumulation of cholesterol, GSLs, and sphingosine.

In contrast to adult nonTg mice, old nonTg mice showed delayed learning performance in terms of latency (F[1,98] = 5.74, p = 0.0167; repeated measures two-way ANOVA) and error score score (F[1,98] = 11.42, p = 0.0008; repeated measures two-way ANOVA) [5], [15], but not in terms of distance (Figure 2A, 2B, and 2C).

MHC-null mice showed delayed remyelination and demyelination.

K6a knockout mice showed delayed re-epithelialization after skin wounding (Wojcik et al. 2000).

In the Morris water maze test, Rgs7 −/− mice showed delayed escape latencies and reduced success rates during acquisition trials.

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