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Exact(6)
In contrast, ankyrin-B+/− cardiomyocytes exhibited 15% basal shortening (n = 4 mice), a value significantly greater than that of unloaded wild-type cardiomyocytes (p<0.01).
Affected mice were given a value of one and unaffected mice a value of zero.
Louboutin et al. (1993) reported a percentage of about 40% internally nucleated myofibres in diaphragm of 120 and 270 days old mdx mice, a value similar to our findings (35.94 ± 5.93%).
The T r was estimated to be 81 hours in mice, a value slightly higher than a T r of 72.3 hours 15 reported for rats treated with recombinant human erythropoietin.
This is supported by an earlier report [ 51] where the major neurotoxic fraction of MOh venom, purified by ion-exchange chromatography and accounted for ~23%% venom weight, has an i.v. LD50 of 0.23 μg/g mice, a value disproportionally lower than that of the crude venom (> 1 μg/g).
The predicted half-life of endogenous plasma EPO (ln2/ kdeg, EPO plasma) is about 1.8 hours for mice, a value lower than that of rHuEPO (epoetin alpha) in rats (t 1/2 = 2.5 hours) and dogs (t 1/2 = 7.2 hours) as published elsewhere.
Similar(54)
ADR induced severe albuminuria, thus leading to values ranging from 23 to 226 mg/mgCr in BALB/cj mice and a value of 0.04 mg/gCr in B6/D2 mice [ 30].
Concerning the intensity of the obtained effect, for example, in skeletal muscle, atenolol decreased the PI of Old-AT mice to a value similar to that of mammals with a fivefold higher longevity (14.7 years) according to data in Fig. 7A from Hulbert et al. (2007).
A single Pink1+/− mouse showed a value of 0.52 (63% of wildtype), while Pink1−/− mice yielded an average signal of 0±0 (n = 6).
Statistical comparisons of IOP profiles generated from these strains utilize nonparametric data comparisons, with data grouped according to empirically set points relevant to these studies: 19 mmHg (i.e. > 2 SD above the mean for young pre-glaucomatous D2 mice) and 21 mmHg (a value commonly regarded as glaucoma suspect in humans) [ 41].
In a study of another arvicoline rodent, the prairie vole, about one third of random genomic fragments sequenced from the BAC library could have been mapped to the mouse genome [ 44], a value similar to that obtained for singletons in our study.
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