Sentence examples for mice a valuable from inspiring English sources

Furthermore, through the generation and use of conditional-KO mice with specific deletion of JAM-C in SCs, we provide conclusive evidence for the involvement of SC JAM-C in regulation of neural functions and acute mechanical pain, rendering these mice a valuable tool for further investigations of the functions of JAM-C in peripheral nerves and in the pathophysiology of peripheral neuropathies.

Because of the relative similarity between the mouse and human genome, knockout mice provided a valuable framework for the development of treatments and therapies for the diseases and disorders that they modeled.

The present study therefore indicates that vitamin A depletion mice are a valuable animal model for studying the role of vitamin A in regulating a range of behavior in mice, and for investigating the involvement of vitamin A signaling in important neurotransmitters pathways such as glutamate signaling.

Genetically engineered mice are a valuable resource for studies of the behavioral effects of ethanol.

Here, we demonstrate that genetically engineered Atp7b−/− mice represent a valuable model for dissecting the disease mechanisms.

Thus, these bacterial artificial chromosome humanized HO-1 mice are a valuable model to study the human HO-1 gene, providing insight to the in vivo architecture of the gene in acute kidney injury and other diseases.

Our results support the notion that in vitro cultures derived from Disc1Tm1Kara mice provide a valuable model for future mechanistic analysis of the cellular and biochemical effects of this mutation, and can thus serve as a platform for drug discovery efforts.

The novel S100A9 KO mice are a valuable tool in this research area.

These knock-in αB-R120G mice are a valuable model of the developmental and molecular biological mechanisms that underlie the pathophysiology of human hereditary cataracts and myopathy.

Our mice provide a valuable in vivo model system to explore MUC16 function in other physiological and pathological conditions such as ovarian carcinogenesis.

This unique dataset, which includes whole-genome expression patterns from 144 mice, provides a valuable resource for the investigation of gene expression patterns associated with a single dietary intervention.