Exact(4)
Swiss Black SP-A−/− mice (a gift of J. Whitsett/T.
Ermilov et al., in preparation ;[44]) and with LSL-KrasG12D mice (a gift from David Tuveson referred to as KrasG12D throughout the text) ([31]) to generate either double or triple mutants: Pdx-Creearly;KrasG12D, Pdx-Creearly CLEG2 Pdx-Creearly CLEG2LEG2;Krand12D.
The c-Myc constitutive knock-out mice were generated by crossing more-Cre and c-Myc floxed/floxed mice (a gift of I.M. de Alborán) to delete the floxed c-Myc allele and then back-crossing to wild-type to remove more-Cre.
C57BL/6 mice, MyD88-deficient mice (a gift from Shizuo Akira, Osaka University, Osaka, Japan), and TRIF×MyD88 doubly deficient mice were bred at CRUK.
Similar(56)
For the PKD1 mouse model, PKD1flox/flox mice were crossed with PKD1+/− OMPcre [20] mice (PKD1flox/flox mice were a gift from Stefan Somlo; OMPcre mice were a gift from Jane Roskams and Stefan Somlo).
H1-receptor gene deficient mice and H2-receptor gene deficient mice were a gift from Prof. Kazuhiko Yanai, Tohoku University [15, 16], and the progeny of the colony was maintained.
C57BL/6J and B6.129P2-Lyz2tm1(cre)Ifo/J mice were purchased from The Jackson Laboratory and the MET floxed mice were a gift from Dr. Snorri Thorgeirsson[38].
Floxed Arid1a mice were a gift from Dr. Peri Tate, Sanger Institute, Hinxton UK; ROSA26 Cre-ERT2 mice were a gift from Prof Chambon, IGBMC, France.
K5Cre mice were a gift from Angel Ramirez and Jose Jorcano and detailed information on control (K5Cre+/tg) SKH-1 mice have been described.
Frozen C57Bl/6 mouse livers from 3 different young (7 month) and 3 different older (17 month) mice were a gift from Dr. Rafael de Cabo (NIA).
LTH1 mice were a gift from Diane Mathis (Harvard).
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