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Quality assessment indicated these methodological weaknesses, which could weaken the internal validity.
Although the quality of the included studies was relatively high, there were still methodological weaknesses which should be taken into consideration.
However, many of the studies measuring outcomes of HIV/AIDS orphans are characterized by specific methodological weaknesses which necessitates caution when interpreting and comparing findings.
Reviews show, however, that most previous studies suffer from methodological weaknesses, which may explain why consistent predictors have not been identified [ 17, 18].
Furthermore, to compensate for methodological weaknesses which arose from the lack of consideration of background differences between pre- and post-characteristics, confounding factor (such as marital status and housing tenure -adjusted DIDs were implementenure -adjustedvity analysis (see supplementary DIDs).
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He pointed to a variety of methodological weaknesses (many of which have been addressed in subsequent papers by Jaeggi and others) and then presented the results from his own attempt to replicate the study, which found no effect whatsoever.
We provide QUADOMICS as a tool that allows systematic reviewers and other readers to identify potential methodological weaknesses in a study, which could have biased the diagnostic accuracy, and therefore judge themselves whether study results are valid.
All results, positive and non-positive, should therefore be considered together with the methodological weaknesses of the studies which could have lead to spurious results.
[ 7] However the evidence identified was mostly published in the United States, and frequent methodological weaknesses limited the conclusions which could be drawn.
Because of these ambiguities and some methodological weaknesses with the scales, which are beyond the scope of this paper, it is important to elicit directly from individuals with schizophrenia how their experience of the disorder affects their HRQoL.
Possible explanations for these 'very low' and 'low' levels include the improved management of these health conditions or treatments, and methodological weaknesses such as confounding effects, which make it difficult to conclude on individual risk factors.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com