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In this paper we present some of the methodological issues which explain the large variability of the reported findings.
However, it is associated with a decrease in the understanding of important methodological issues which may lead to inappropriate translation of the results into clinical practice.
One of the major methodological issues which arises when quantitatively comparing DRG systems across countries, is variation in purchasing power between nations.
In this paper, we discuss the theoretical and methodological issues which have an influence upon the construct validity of employment interviews.
Replication also drew attention to a number of methodological issues which deserve consideration when using simulation to test the effectiveness of clinical tools and the need to establish adequate measures of external validity whenever use of this method is contemplated.
The conclusion suggests that this normative content may provide guidance for the design, implementation, and evaluation of real-life science policy interfaces, and identifies key methodological issues which need further theoretical research as well as practical experimentation.
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It should be acknowledged, however, that the value of this parameter can have a potentially substantial impact both on the model's prediction accuracy and the reproducibility of its spatial discrimination pattern; this is an outstanding methodological issue which is discussed in detail elsewhere [Rasmussen et al., 2012].
Special consideration is given to the methodological issues of which risks should be taken into account when considering an integral assessment.
However, there are some common methodological and statistical issues which may ignore by authors.
In the final section, though, we will briefly discuss some further methodological and epistemological issues which arise.
Such an approach raises logistic, methodological and ethical issues which we shall briefly consider here.
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