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Overall up-regulation of metabolic pathways contributing precursors to storage lipid biosynthesis was observed in S. dimorphus.
These observations suggest that key signaling and metabolic pathways contributing to the cellular response to cigarette smoke and oxidants are downregulated in the lungs of smokers with cancer.
The different signaling and metabolic pathways contributing to synaptotoxicity and neurodegeneration in AD are being comprehensively focused which can serve as effective molecular targets.
In this scenario, it is tentative to propose that defects in gangliosides synthesis may alter the flow of the lipids through the metabolic pathways contributing to disruption in cellular physiology.
Furthermore, the remarkably high level of differential expression of the gene encoding a putative pyruvate kinase and a homeodomain transcription factor in transgenic seeds indicates that DGAT over expression may also affect upstream metabolic pathways contributing to the biosynthesis of fatty acids, to be incorporated into TAGs.
In this work, the differences in leaf gene transcripts, proteins and metabolite accumulation in gln1.3 and gln1.4 mutants were studied at two key stages of plant development, in order to identify putative candidate genes, proteins and metabolic pathways contributing on one hand to the control of plant development and on the other to grain production.
Similar(54)
Dysregulation of metabolic pathways contributes to many diseases, so a detailed understanding of human metabolism has significant therapeutic implications.
The natural coordination among different metabolic pathways contributes to the complexity of metabolic modification, which hampers the development of biorefineries.
Komurov et al. [ 17] hypothesized that cross-talks between EGFR/ErbB signaling and metabolic pathways contribute to resistance to lapatinib.
Transporters involved in metabolic pathways contribute to the direct rerouting of cellular resources by the internalized bacterium.
In tissues of patients with the peroxisomal disorder X-linked adrenoleukodystrophy (X-ALD), both metabolic pathways contribute to the accumulation of VLCFA [ 22].
Related(16)
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