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In our study, a metabolic reconstruction integrating the best-known metabolic pathways participating in cancer development was accomplished: glycolysis, pentose phosphate pathway, oxidative phosphorylation, glutaminolysis and TCA cycle.
In this work we present a constraint-based analysis of a metabolic network integrated by a core of metabolic pathways participating in cancer cell growth: glycolysis, TCA cycle, pentose phosphate pathways (PPP) and oxidative phosphorylation.
To further delineate the metabolic pathways participating in the dehydration and rehydration responses, we mapped the DTGs into the Kyoto Encyclopedia of Genes and Genomes (KEGG) database.
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When possible, Blast2GO also provides Enzyme commission (EC) numbers and the metabolic pathways they participate.
Rapeseed contains various components and many genes are involved in different metabolic pathways to participate in the formation of oil content.
By performing parallelised construction of biochemical models, for instance, models for metabolic or signalling pathways participated by some key species, much more biochemical meaningful models can be obtained and further investigated by biologists in wet laboratory.
The Ras signaling pathway is arguably the most intensively studied pathway participating in the metabolic reprogramming that actively contributes to tumorigenicity.
We also performed enzyme code (EC) annotation through Blast2GO for sequences with GO annotations and retrieved KEGG maps for the metabolic pathways in which they participate.
The reactions catalyzed by proline racemase (ProR), 4R-hydroxyproline 2-epimerase (4HypE), and trans -3-hydroxy-L-proline dehydrathee ( t 3HypD) and the metabolic pathways in which they participate.
In addition, by categorizing genes into Biological Process ontologies as well as KEGG metabolic pathways in which they participate, we analyzed the behavior of groups of genes involved in these categories.
Long-chain FA (LCFA) are esterified with CoA in the inner face of the plasma membrane prior to participating in metabolic pathways.
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