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This transcriptomics-based method allows the identification of genes involved in a defined metabolic pathway based on their co-expression with genes of known function, through the assumption that genes involved in the same biochemical pathway are co-regulated 34.
Several markers that are associated with the metabolites studied, were also identified in QTL studies for the same metabolites in DH populations derived from crosses between two accessions (yellow sarson (YS 143) x pakchoi (PC 175) and their reciprocal cross (Table S3), or map to regions that harbour structural genes in the metabolic pathway based on Arabidopsis-B.
KEGG metabolic pathway based analysis further revealed several lifestyle specific preferences (secretion systems) across pseudomonad genomes (n = 18).
We provide a systematic graphic representation of regulations of each metabolic pathway based on the central role of metabolites in regulation.
In a previous paper, we presented a method for constructing a kinetic model for a metabolic pathway based only on the knowledge of its stoichiometry [ 5].
Additionally, many genes connected to synthesis and degradation of triacylglycerol (TAG; metabolic pathway based on [ 73]) are regulated mainly in response to limiting glucose, which probably leads to the accumulation of free fatty acids which can then be degraded by beta-oxidation.
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Here we review synthetic metabolic pathways based on fatty acid and isoprenoid metabolism to produce alkanes and other molecules suitable as biofuels.
The carbon in glucose and fructose is further channeled into various primary or secondary metabolic pathways based on the spatiotemporal activity of metabolizing enzymes [ 2- 4].
To examine the potential for modification of metabolic pathways based on thermodynamic principles we have performed simple molecular dynamics simulations, in vacuo and in aquo on the metabolites synthesized by recombinant polyketide synthases (PKS).
In this paper, we review different computational approaches used to design metabolic pathways based on the reaction network representation of the database (i.e., graph or stoichiometric matrix) and the search algorithm (i.e., graph search, flux balance analysis, or retrosynthetic search).
The optimized relative positions of KEGG metabolic pathways based on the total intensities of metabolites within each pathway thus provides a relatively robust coarse-grained pattern of silkworm metabolic activity around ecdysis (Fig. 5b d).
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metabolic route based
metabolic pathway used
metabolic approach based
metabolic pathway causes
metabolic simplification based
metabolic yield based
metabolic design based
metabolic response based
metabolic network based
metabolic flux based
metabolic shift based
metabolic capacity based
metabolic model based
metabolic branching based
metabolic activity based
metabolic abnormality based
metabolic information based
metabolic pathway achieved
metabolic labeling based
metabolic enzymotherapy based
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