Sentence examples for membrane potential so from inspiring English sources

However, effects of a positive charge on overall conformational change may be realized only when the charge moves along the electrostatic field of the membrane potential so that its electrostatic energy is converted to conformational energy of the protein.

A limit cycle is obtained when there is no threshold operation applied to the membrane potential, so that the three-dimensional dynamical system of the membrane potential is attracted to its stable trajectory (Appendix S1, Eq. 5).

Because of the presence of uricase, the urate chemical gradient overcomes the membrane potential so that SLC2A9 can transport urate into liver cells.

We also showed that the resonance behavior in the HH-type model depends on membrane potential, so that the strong hyperpolarizing resting potential causes the disappearance of resonance frequency, and the depolarizing resting potential increases their frequencies.

Superoxide production by mitochondria isolated from mammals (Liu, 1997; Korshunov et al., 1997) or Drosophila (Miwa et al., 2003) can be acutely sensitive to membrane potential, so if mitochondrial superoxide production contributes to ageing, mild mitochondrial uncoupling might extend lifespan.

Oxidative phosphorylation is uncoupled when the mitochondrial membrane potential depolarises so that ATP can no longer be synthesised leading to ATP depletion and necrotic cell death.

1,  2 Second harmonic generation (SHG) is one of the most promising methods for imaging membrane potential, although so far this technique has only been demonstrated with a narrow range of dyes. 3 Here we show that SHG from a porphyrin-based membrane probe gives a fast electro-optic response to an electric field which is about 5 10 times greater than that of conventional styryl dyes.

In fact, our results show that mitoQ does, in fact, reduce membrane potential (figure 9), so this may explain the effect of mitoQ to reduce ROS generated by mitochondria respiring on succinate.

The magnitude of ROS production is largely dependent on the proton-motive force across the inner membrane (membrane potential, or ΔΨ), so it can be strongly decreased by proton leak-induced mild uncoupling of mitochondrial OxPhos [ 54].

The dye responds quickly to changes in membrane potential (within 5 microseconds), so follows the kinetics of action potentials faithfully (although there may be noise in the signal).

It is thought that C. elegans neurons are generally isopotential (Goodman et al. 1998), so membrane potential could provide the long-range signal necessary to communicate from one Ca2+ compartment to another.