This implies that synaptic update rules for short-term or long-term plasticity can only depend on spike timing and, potentially, on membrane potential, as well as on the value of the synaptic weight, or on low-pass filtered (temporally averaged) versions of the above variables.
The mechanism of cell death induced after PDT was determined by measuring caspase 3 activation, DNA fragmentation, phosphatidylserine externalization, mitochondrial morphological changes and loss of mitochondrial membrane potential as well as lysosomal membrane integrity.
The experimental results for the membrane potential agree well with the theoretical predictions if the effective charge densities of bipolar membranes were assumed to be 0.0001 times smaller than those which were estimated for each layer separately.
Here, we first investigated the effect of C60 COOH on mitochondria dynamics, showing that C60 COOH treatment prevents mitochondria fragmentation, depolarization of mitochondria membrane potential, as well as attenuation of NF-κB and MAPK activation, thus leading to reduced neuroinflammatory response.
In their work, they showed that single-walled carbon nanotubes (SWNTs) were found to be non-toxic when using assays such as LDH, annexin V, and PI staining, mitochondrial membrane potential, as well as other tetrazolium salt-based water-soluble assays such as WST-1, XTT, or INT.
In contrast, CTMP knockdown resulted in a marked reduction in the loss of mitochondrial membrane potential as well as a decrease in caspase-3 and PARP activation.
While ipRGCs are subject to ionotropic GABA and glycine-gated inhibitory currents [19], [20], these probably do not hyperpolarize the membrane sufficiently to activate Ih because the Cl− reversal potential presumably lies close to the resting membrane potential and well positive to the Ih activation threshold.
They maintain their membrane composition, organization and membrane potential, as well as the ability to fuse [ 12] and to import proteins [ 7].
A truncated form of p30, p13 localises in mitochondria and alters membrane potential as well as reactive oxygen species (ROS) production (Silic-Benussi et al, 2009).
Moreover, capsaicin induced disruption of the mitochondrial membrane potential as well as activation of caspase 9, 3 and poly- ADP-ribose) poly- ADP-ribose cells.
