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On the contrary, in breast [24] [26] and ovarian cancer [20] ALCAM cytoplasmic overexpression and low membrane expression were associated with disease progression.
CL production and CD11b membrane expression were significantly lower than in supernatants obtained without the peptides.
Eighteen of 90 (20.0%) patients with 2+ or 3+ Her2 membrane expression were AP-2α/β positive.
Moreover, p53 expression and Fas membrane expression were strongly upregulated after treatment with MDM2 siRNA in combination with cisplatin, especially in the cisplatin-resistant TC cells.
Variable degrees of PD-L1 surface membrane expression were also detected on immune cells, specifically histiocytes (macrophages) and lymphocytes, and when present were recorded in accord with the principles set forth by the "Immunoscore Consortium".
Similar(55)
No induction of Fas membrane expression was observed in the mutant p53-expressing NCCIT after the various treatments (Supplementary Figure 3b).
Induction of Fas membrane expression was not detected in the mutant p53-expressing NCCIT cells after cisplatin or Nutlin-3 treatment (Supplementary Figure 3b).
Intestinal absorption and renal reabsorption of phosphate are mediated by members of the SLC34 family of sodium-coupled transporters (NaPi-IIa,b,c) whose membrane expression is regulated by various hormones, circulating proteins, and phosphate itself.
Decreased/lost ALCAM membrane expression is a marker of poorer outcome in epithelial ovarian cancer.
Membrane expression of E-cadherin was observed after 1 day in 3D culture [22], whilst Dsg2 membrane expression was not seen until day 4 (Figure S2C).
Kv12.2 channel membrane expression was assessed by membrane surface biotinylation assay utilizing a 'Cell surface protein isolation kit' (Pierce, IL), according to instructions from the manufacturer.
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