Sentence examples for mediators that inhibit from inspiring English sources

Dying neutrophils secrete mediators that inhibit further neutrophil recruitment.

In normal tissue, myoepithelial cells control mammary gland homeostasis by forming a physical barrier between epithelial cells and the surrounding stroma and secreting paracrine mediators that inhibit cell migration [ 55].

The purpose of this study was to determine whether PBMC isolated from patients with SSc and cultured in vitro with soluble CI elaborated soluble mediators that inhibit the production of collagenase (i.e., matrix metalloproteinase, MMP-1) by fibroblasts.

Another critical process for the initiation of parturition involves the transition of the uterus from a quiescent tissue, influenced by mediators that inhibit contraction, to a synchronously contracting tissue.

The picture of hyperglycemia and insulin resistance observed in sepsis, often referred to as "stress diabetes," reflects the activation of signaling pathways and hyperexpression of inflammatory mediators that inhibit insulin action [ 44].

Arachidonic acid-stimulated trypomastigotes released high amounts of prostaglandin E2, which results from arachidonic acid breakdown and acts as a potent immune modulatory lipid mediator that inhibits many aspects of innate and adaptive immunity.

PGE2 is a powerful mediator that inhibits T cell mitogenesis and IL-2 production [ 47]. Park et al. recently reported that TGF-β1-transduced MSCs, but not control MSCs, suppressed the development of type II collagen-induced arthritis (CIA).

Our recent Rnd3 genetic mouse study demonstrated that Rnd3 is a novel mediator that inhibits Notch signaling by facilitating the ubiquitination of the Notch active isoform, NICD, in the mouse brain.

Luminal nutrients stimulate enteroendocrine cells (EEC) to release mediators that potently inhibit appetite and promote glucose homeostasis.

The activation of NF-кB by BST-2 results in increased production of immune-inflammatory mediators that may inhibit viral replication [ 13], but may also promote tumorigenesis.

It is believed that the therapeutic effects of nicotine in IBD are mediated by the nicotinic acetylcholine (ACh) receptors (nAChRs) of gut immune cells that inhibit production of inflammatory mediators and correct specific alterations in cell cycle responses [ 18– 20].