Sentence examples for mediators that play from inspiring English sources
The soluble epoxide hydrolase (sEH) is involved in the metabolism of arachidonic, linoleic, and other fatty acid epoxides, endogenous chemical mediators that play an important role in blood pressure regulation and inflammation.
Exchange proteins directly activated by cAMP (EPACs) are critical cAMP-dependent signaling pathway mediators that play important roles in cancer, diabetes, heart failure, inflammations, infections, neurological disorders and other human diseases.
The asthma pathophysiology involves chemical mediators that play an important role in the establishment of inflammation.
One of the mediators that play an important role in the inflammatory process is TNF-α.
They are bioactive inflammatory lipid mediators that play a key role in immunity and immunopathology.
FLS produce various inflammatory mediators that play important roles in development of RA.
We observed an increase in SOCS1 protein levels during SLE progression, suggesting that SOCS1 is a cytoplasmic mediator that plays a role in this pathway-specific regulation (Fig. 4C E).
Furthermore, fibrin is a proinflammatory mediator that plays an important role in leukocyte recruitment to inflamed tissues, and this may also damage lung tissues [ 42].
This cytokine is a potent anti-inflammatory mediator that plays a role in attenuating inflammatory responses and suppressing the expression of proinflammatory cytokines [ 44].
Tumor necrosis factor-alpha (TNF- α) is a potent proinflammatory and proapoptotic mediator that plays an important role in several normal and disease processes by activating several different signaling pathways.
For example, a tumour suppressor gene, p53, is a key DNA damage mediator that plays a dual role following exposure to cytotoxic treatment (Ferrera et al, 1999); it is involved in damage-induced apoptosis, but also plays a role in cell cycle arrest and DNA repair, cellular processes that can affect the sensitivity to chemotherapeutic drug.
