Sentence examples for mediators that transduce from inspiring English sources

PUMA is one of the most potent mediators that transduce death signals primarily to mitochondrion.

Since COX catalyzes the opening reaction required for the biosynthesis of all PG subtypes, one major question regards the identity of the lipid mediators that transduce the pro-carcinogenic effects of COX.

Omega-3 PUFAs electrophilic derivatives appear to be the active mediators that transduce the beneficial actions observed upon dietary administration of omega-3 PUFAs and therefore there has been a growing interest in characterizing their formation and signaling actions in health and disease.

Integrins are critical mediators of cell ECM interactions that transduce extracellular signals into the intracellular network through integrin-mediated signaling molecules, including epidermal growth factor receptor (EGFR), focal adhesion kinase (FAK) and phosphatidylinositol 3-kinase (PI3K).

It will be of key interest to investigate the interrelationships between these activities and to define the effectors and downstream mediators that are involved in RhoA-and Rac1-transduced mitogenesis, transformation and invasiveness.

Mechanical strain imposed on airway cells induce a cascade of signaling events, primarily mediated by the macromolecular protein complexes associated with the transmembrane integrins that transduce the external forces from the extracellular matrix to the actin cytoskeleton, resulting in the production of various mediators, cytokines, and growth factors, coupled with gene activation [ 6, 7].

Cell classifiers are genetic logic circuits that transduce endogenous molecular inputs into cell-type-specific responses.

G protein-coupled receptors (GPCRs) are a class of versatile proteins that transduce signals across membranes.

Integrins are cell surface receptors that transduce signals bidirectionally across the plasma membrane.

However, most of the components that transduce stress signals remain to be discovered and elucidated.

Frizzleds are seven-pass transmembrane (7TM) receptors that transduce critical cellular signals during development.