Sentence examples for mediating the proliferation from inspiring English sources

Although the chondrogenic response of periosteum is well established in healing fractures, the mechanisms mediating the proliferation and differentiation of periosteal chondroprogenitor cells are poorly understood.

THs influence neurogenesis by mediating the proliferation of neural progenitor cells, influencing dendritic and synapse formation, and regulating myelination (Gould and Butcher 1989; Porterfield and Hendrich 1993).

Consistent with this, expression of CXCL12 by activated astrocytes within the acutely demyelinated CC influences remyelination by mediating the proliferation and differentiation of OPCs.

Although TNF was discovered as a cytokine that could kill tumor cells, it is now clear that TNF can also contribute to tumorigenesis by mediating the proliferation, invasion and metastasis of tumor cells [ 5].

The results of the present study suggest that colXI α1 has a role in mediating the proliferation, invasion, and migration of cancer cells, underscoring the need for further investigation of this collagen in carcinogenesis.

GM-CSF is a hematopoetic growth factor that also modulates immune system activity in a variety of ways, mediating the proliferation and maturation of antigen-presenting dendritic cells 46, 47 and activating monocytes and macrophages.

These results suggest that profilin-1 mediates the proliferation of RASMCs induced by Ang II via activation of Ang II type 1 receptor/JAK2/signalingnaling pathway, which may contribute to vascular remodeling in hypertension.

Furthermore, another selected gene glutathione transferase mediates the proliferation of androgen-independent prostate cancer cells [44].

It is not known whether genetic exchange occurs in populations of T. vaginalis; however, genetic exchange could mediate the proliferation of drug-resistant mutations or increased virulence in populations of the parasite.

Shh is expressed in the cloaca endoderm and mediates the proliferation of urs mesenchyme through Gli2.

Together our results suggest that IVC mediates the proliferation of human cancer cells via downregulating the Rho/ROCK pathway.