Sentence examples for mediate the proliferation from inspiring English sources
It is not known whether genetic exchange occurs in populations of T. vaginalis; however, genetic exchange could mediate the proliferation of drug-resistant mutations or increased virulence in populations of the parasite.
The upregulation of miR-1246 couldownregulatethethexpressionon levels of its target genes to mediate the proliferation, invasion, and migration of cancer cells [ 34- 36].
Thus, it is understood that, in rheumatoid arthritis synovial fibroblasts, TNF-α induces apoptosis only when signalling pathways that mediate the proliferation are blocked [ 12].
In NSCLC, the IGF-IR has been shown to be frequently expressed in tumour tissue as well as to mediate the proliferation of lung cancer cell lines (Favoni et al, 1994).
Furthermore, TP53INP1 might be a target gene of miR-155 in fibroblasts, which may mediate the proliferation and the activation of normal fibroblasts, and manifest the characteristics of CAF.
Observations utilizing two-dimensional cell cultures in vitro have been critical in elucidating the genetic programs and signaling pathways that mediate the proliferation and hormonal response of malignant epithelial cells in breast cancers.
Although the chondrogenic response of periosteum is well established in healing fractures, the mechanisms mediating the proliferation and differentiation of periosteal chondroprogenitor cells are poorly understood.
These results suggest that profilin-1 mediates the proliferation of RASMCs induced by Ang II via activation of Ang II type 1 receptor/JAK2/signalingnaling pathway, which may contribute to vascular remodeling in hypertension.
Furthermore, another selected gene glutathione transferase mediates the proliferation of androgen-independent prostate cancer cells [44].
Shh is expressed in the cloaca endoderm and mediates the proliferation of urs mesenchyme through Gli2.
Together our results suggest that IVC mediates the proliferation of human cancer cells via downregulating the Rho/ROCK pathway.
