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Levels of Th2 cytokines (IL-4, IL-5, IL-13) in the lymph nodes or spleen were significantly decreased while those of Th1 cytokine (IFN-γ) were increased in ZY12 treated group, suggesting a protective role of ZY12 in AC by mediating the balance of Th1/Th2 cytokines.
Matrix metalloproteinases are known to play a critical role in atherosclerosis and cardiovascular tissue remodeling, mediating the balance between matrix accumulation and degradation [27].
NO is key in mediating the balance of pro- and antiinflammatory cytokines in the DEP-exposed lung.
The Hippo signaling pathway controls organ size by mediating the balance between proliferation, differentiation and apoptosis in cells.
However, the importance of intrinsic Treg, which are constantly mediating the balance of the homeostasis at the mucosal barrier in the colon, for the development of acute and chronic intestinal inflammation is accepted, yet mechanistically rather unclear.
Similar(55)
They are generally used to target the innate immune response, which further facilitate the evolution of the adaptive immune response (Pashine et al., 2005; Reed et al., 2009) and mediate the balance between humoral and cellular immunity (Brunner et al., 2010).
What synaptic mechanisms mediate the balance between protecting proteins and preventing accumulation of misfolded proteins remains a current biological question.
Signalling pathways evoked in cancer cells by the surrounding environment can mediate the balance between antiangiogenic and proangiogenic VEGF isoforms [ 50, 51].
These results identified mex3-1 as a cell fate regulator, broadly required for differentiation, and suggest that mex3-1 helps to mediate the balance between ASC self-renewal and commitment.
SphK mediates the balance between the proapoptotic effects of ceramide and sphingosine substrates and the antiapoptotic effects of sphingosine-1-phosphate (S1P), a phosphorylation balance system more aptly named "the sphingolipid rheostat" [ 18, 36, 37].
Allosteric mechanisms at least in part mediate the balance between how the proton gradient is utilized and how flux is split between glycolysis and the PPP; the enzyme glucose-6-phophate-1-dehydrogenase, which catalyzes the first reaction of the PPP, is allosterically inhibited by NADH.
Related(20)
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mediating the representation
negotiating the balance
mediating the stability
mediate the balance
mediating the impact
mediating the effect
mediating the semantization
mediating the dispute
mediating the inflammation
mediating the activation
mediating the journey
mediating the building
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mediating the production
mediating the response
mediating the inhibition
mediating the cell
mediating the adsorption
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