Sentence examples for mediate the balance from inspiring English sources

They are generally used to target the innate immune response, which further facilitate the evolution of the adaptive immune response (Pashine et al., 2005; Reed et al., 2009) and mediate the balance between humoral and cellular immunity (Brunner et al., 2010).

What synaptic mechanisms mediate the balance between protecting proteins and preventing accumulation of misfolded proteins remains a current biological question.

Signalling pathways evoked in cancer cells by the surrounding environment can mediate the balance between antiangiogenic and proangiogenic VEGF isoforms [ 50, 51].

These results identified mex3-1 as a cell fate regulator, broadly required for differentiation, and suggest that mex3-1 helps to mediate the balance between ASC self-renewal and commitment.

Interestingly, and in line with these observations, the expression levels of negative regulators of TLR signaling such as Ptpn11 and Pparg was conversely increased in congenics, suggesting that the arthritis gene located within the Cia5a QTL might mediate the balance between activating and inhibitory signals implicated in TLR signaling.

Allosteric mechanisms at least in part mediate the balance between how the proton gradient is utilized and how flux is split between glycolysis and the PPP; the enzyme glucose-6-phophate-1-dehydrogenase, which catalyzes the first reaction of the PPP, is allosterically inhibited by NADH.

Levels of Th2 cytokines (IL-4, IL-5, IL-13) in the lymph nodes or spleen were significantly decreased while those of Th1 cytokine (IFN-γ) were increased in ZY12 treated group, suggesting a protective role of ZY12 in AC by mediating the balance of Th1/Th2 cytokines.

Matrix metalloproteinases are known to play a critical role in atherosclerosis and cardiovascular tissue remodeling, mediating the balance between matrix accumulation and degradation [27].

The Hippo signaling pathway controls organ size by mediating the balance between proliferation, differentiation and apoptosis in cells.

NO is key in mediating the balance of pro- and antiinflammatory cytokines in the DEP-exposed lung.

However, the importance of intrinsic Treg, which are constantly mediating the balance of the homeostasis at the mucosal barrier in the colon, for the development of acute and chronic intestinal inflammation is accepted, yet mechanistically rather unclear.