Sentence examples for mediating efflux of from inspiring English sources

The Neo-Urinary Conduit™ is a tubular neo-organ composed of native-like urinary tissue mediating efflux of urine from the body in patients requiring urinary diversion.

It was first identified in human and rat hepatocytes, mediating efflux of organic anions into sinusoidal blood.

Thirteen MRPs have so far been identified within the human genome, although MRP1 (also known as ABCC1) and MRP4 are considered most efficient in mediating efflux of sulfated steroids.

The multidrug-resistance gene 1 (MDR1) gene represents an interesting candidate for PSC susceptibility due to its role as membrane transport protein mediating efflux of a wide range of xenobiotics and toxins [40] and MDR1 gene variants may be associated with IBD disease progression and severity [41].

The aim of our study was to provide a microelectrode method for measuring the multidrug transporter mediated efflux of doxorubicin as well as a corresponding data analysis method for quantifying the efflux kinetic parameters.

In olfactory cilia, ANO2 may mediate efflux of chloride ions following calcium entry through cyclic nucleotide-gated channels, thereby amplifying the magnitude of the depolarizing signal in response to odorants [21], [23].

This may be related to the presence of an efflux protein that mediates efflux of antibiotics and chemicals from mycobacterial cells (Doran et al. 1997).

MDR1 (also known as P-glycoprotein) is an ATP-dependent transporter that mediates efflux of drugs and toxins from the cell.

PHT1 is hypothesised to mediate efflux of bacterial-derived peptides into the cytosol perhaps in the colon where SLC15A4 mRNA expression is increased in inflammatory bowel disease 259.

These P-type ATPases have been suggested to either sequester cisplatin in vesicular structures or to mediate efflux of the drug [ 11, 12].

For example, blood-to-brain transport of Tyr-MIF-1 Tyr-MIF-1 Tyr-MIF-1 is very limited becande of the action of PTS1 in thenkephalins membrane of BECs, whish mediates efflux of those peptides [ 168].