Sentence examples for mediate efflux of from inspiring English sources

In olfactory cilia, ANO2 may mediate efflux of chloride ions following calcium entry through cyclic nucleotide-gated channels, thereby amplifying the magnitude of the depolarizing signal in response to odorants [21], [23].

Apical potassium channels lead to an influx of K+ while basolateral channels likely mediate efflux of K+.

These P-type ATPases have been suggested to either sequester cisplatin in vesicular structures or to mediate efflux of the drug [ 11, 12].

PHT1 is hypothesised to mediate efflux of bacterial-derived peptides into the cytosol perhaps in the colon where SLC15A4 mRNA expression is increased in inflammatory bowel disease 259.

The MRPs mediate efflux of organic anions such as GSH at the expense of cellular ATP while the Oatps catalyses the uptake of organic anions in exchange for GSH [ 73].

One well-known mechanism of chemoresistance is up-regulation of ABC transporters, which mediate efflux of the anti-cancer drugs [ 37– 39]; expression of one ABC transporter, ABCG2, was up-regulated in SK-sphere cells.

The Neo-Urinary Conduit™ is a tubular neo-organ composed of native-like urinary tissue mediating efflux of urine from the body in patients requiring urinary diversion.

The aim of our study was to provide a microelectrode method for measuring the multidrug transporter mediated efflux of doxorubicin as well as a corresponding data analysis method for quantifying the efflux kinetic parameters.

It was first identified in human and rat hepatocytes, mediating efflux of organic anions into sinusoidal blood.

The SOS pathway mediates efflux of Na+ cross the plasma membrane to the soil solution or apoplast.

This may be related to the presence of an efflux protein that mediates efflux of antibiotics and chemicals from mycobacterial cells (Doran et al. 1997).