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The Intimin/Invasin (Int/Inv) family of adhesins (TC# 1.B.54) consists of outer membrane (OM) proteins that mediate bacterial attachment to and/or invasion of their host cells [3], [4].he archetypal members of the Int/Inv family are from strains of pathogenic Escherichia coli (Int) and Yersinia spp. (Inv).
These include adhesins and membrane proteins that mediate bacterial attachment, colonization, and invasion of host cells.
Afa/Dr adhesins mediate bacterial attachment onto target cells by binding to the complement regulatory glycosylphophatidylinositol- GPI- anchored protein DAF [ 166].
B. burgdorferi decorin-binding proteins (Dbp) A (BB_A24) and B (BB_A25) are mainly expressed during mammalian infection to mediate bacterial attachment to the proteoglycan decorin in decorin-expressing mammal cells.
Hence, our CFM data demonstrate that (i) P. aeruginosa type IV pili mediate bacterial attachment to hydrophobic surfaces, and (ii) they are mechanically strong as they can sustain forces up to 250 pN.
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Understanding the way by which the substratum topography, especially at the nanoscale, mediates bacterial attachment remains ambiguous at best, despite the volume of work available on the topic.
DEC-205, for example, is a member of the mannose receptor family and binds to plasminogen activator (PLA) on the surface of Yersinia pestis, which mediates bacterial attachment (Lähteenmäki et al., 1998).
Further subcloning revealed that the sequence encoding the 28 amino acids signal peptide of LukS-PV (LukS-PV SP) was sufficient to mediate enhanced bacterial attachment to ECM components.
Tir is the best-studied EPEC effector and is inserted into the host plasma membrane where it acts as a receptor for Intimin, mediating intimate bacterial attachment to the host cell (Kenny et al., 1997).
Figure 2 showed that only the expression of LukS-PV signal peptide can mediate the enhanced bacterial attachment to ECM proteins.
It can precisely mediates site-specific DNA recombination between a bacterial attachment site (attB) and a phage attachment site (attP) without requiring others cofactors, resulting in integration when the two-att sites are present on two different DNA molecules and deletion or inversion when the two-att sites are on the same molecule [2], [3].
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mediate bacterial adhesion
mitigate bacterial attachment
mediate bacterial adherence
mediate strong attachment
mediate cellular attachment
mediate viral attachment
mediate conjugative attachment
mediate bacterial motility
mediate bacterial aggregation
mediate bacterial invasion
mediate bacterial piliation
mediate bacterial clearance
mediate bacterial infection
mediate stable attachment
mediate primary attachment
mediate bacterial internalization
mediate initial attachment
mediate bacterial stress
mediate bacterial cell cell
mediate covalent attachment
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