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EPO may improve microvascular capacity of ischemic myocardial tissue and could thereby (partially) restore myocardial function.
By decreasing NO levels in the cortex, NAC combined with fluid administration may improve microvascular dysfunction, microvascular delivery of oxygen, and cortical oxygenation.
The combination of Levosimendan and INO may improve microvascular perfusion in septic shock.
The current study was performed to test the hypothesis that a combination of levosimendan and inhaled nitric oxide (INO) may improve microvascular perfusion in septic shock.
Indeed, a key observation is that therapeutic modalities that may improve microvascular function are also associated with decreased organ dysfunction and improved outcome in patients with sepsis [ 6- 8].
Although hyperglycemia is strongly associated with the development of microvascular complications, evidence is accumulating to support the notion that dyslipidemia may also play a role and that statins may improve microvascular function (21).
Similar(53)
Correction of severe hypotension does not impair and may even improve microvascular perfusion [33, 34] probably through the restoration of the perfusion of the organs through achievement of a minimal perfusion pressure.
Correction of severe hypotension does not impair and may even improve microvascular perfusion [ 33, 34] probably through the restoration of the perfusion of the organs through achievement of a minimal perfusion pressure.
NAC may still further improve microvascular oxygenation by decreasing endothelial glycocalyx damage in addition to fluid resuscitation.
However, increasing blood pressure further (mean arterial pressure from 65 to 75 and 85 mmHg) may fail to improve microvascular perfusion.
The increased microvascular endothelial cell density of irradiation-induced wound granulation tissue in VT-treated mice suggested that VT may have improved microvascular endothelial cell survival or function.
Related(20)
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may compromise microvascular
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