Sentence examples for may impair microvascular from inspiring English sources
In conclusion, CSDs may impair microvascular function and O2 availability, likely with increased O2 consumption, in human cerebral cortex after SAH, especially if they occur in clusters.
Increased cardiac output and excessive pressure pulsatility associated with diabetes may impair microvascular function, but adverse effects of aortic stiffening on microvascular function also may contribute to the pathogenesis of diabetes-related vascular disease.
All of these diseases may impair microvascular circulation and cause localized ischemia, which increases free radicals and inflammatory cytokines [ 37], and concomitantly alters gene expressions of growth factors, adhesion molecules, and extracellular matrix components that, in turn, trigger the proliferation of DD tissue [ 49].
Despite the necessity of vasopressors to maintain systemic hemodynamics in many patients after ROSC, excessive use of these drugs may impair microvascular function and tissue perfusion, in addition to provoking recurrent arrhythmias and potentially increasing the risk of adverse outcomes [ 36, 128, 129].
Obesity has been shown to impair microvascular recruitment (15).
These last two factors may contribute to impaired microvascular blood flow [ 14, 17, 18], which may affect organ function, especially in the organs acting as natural filters, such as the lung and the kidney.
Collectively, microvascular disease may impair myocardial metabolism during stress, leading to an impaired response to stress, as reflected by impaired DFRI and stress GLS in patients with diabetic retinopathy.
From a theoretical point of view, very high flow may induce shear-stress lesions to the capillary wall, promoting further microvascular lesions, and may impair oxygen offloading.
This observation may indicate that IABP impairs microvascular perfusion in recovered patients, although this warrants confirmation.
Impaired microvascular responses may also diminish muscle insulin uptake, perhaps accounting in part for the muscle insulin resistance seen.
This may impair recovery.
