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Exact(7)
Taken together, these results reinforce the notion that enhanced PrPc-overexpression may impair cell homeostasis in vitro and in vivo.
In NPC cells, EBV may impair cell cycle checkpoint via its encoded lament membrane protein [ 41].
The abnormally elevated level of MMPs may impair cell migration and result in sustained inflammation with net increased tissue destruction.
Thus, the reduced expression induced by milatuzumab in vivo may impair cell migration and prevent their proper participation in immune responses.
In particular, as demonstrated in a different cell model, SI compounds may impair cell adhesiveness and migration through the inhibition of kinases in focal adhesion complex [ 17].
Dysregulation in time and intensity of the expression of the mitochondrial relative to the nuclear genome may impair cell function and reflect a till now neglected mechanism of Ara-C cytotoxicity.
Similar(53)
Stretching lengthens diffusional distances and thereby may impair cell-to-cell communication among epithelial cells.
Acquired or iatrogenic immunosuppression may impair cell-mediated immunity such that tumour-specific lymphocytes are unable to maintain an effective tumour surveillance system.
However, high levels of ER stress or ER dysfunction may also impair cell survival by triggering apoptotic pathways (review by [27].
As these DRM microdomains are involved in many cellular events, an imbalance or disruption of the cell membrane homeostasis may impair normal cell function.
We hypothesised that tumour cells may impair T-cell effector functions through secretion of galectin-1 and that this mechanism may contribute in tilting the balance towards an immunosuppressive environment at the tumour site.
Related(20)
may impair tissue
may impair endometrium
may induce cell
may impair hearing
may impair driver
may impair insulin
may impair flexibility
may impair information
may impair success
may impair organization
may interrupt cell
may impair progress
may impact cell
may impair gut
may optimize cell
may damage cell
may elicit cell
may initiate cell
may promote cell
may impair protein
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