This domino effect may damage cells and potentially play a role in the development of certain conditions such as heart disease and cancer.
Heme iron (also called free iron), found in meat, produces free radicals that may damage cells and trigger cancer.
Nevertheless, NO has the potential to generate free radicals which may damage cells [12] and therefore it is important that NO and iNOS be tightly regulated [49].
Some require red blood cell lysis, which may damage cells.
Indeed, increased levels of TBARS and free radicals found in the study may damage cells as observed by histopathological investigations.
The accumulation of excess lipid, in particular, saturated FA, may damage cells by causing stress on membranes of lipid-metabolizing organelles, especially mitochondria.
29 Neuropathy is a common AE associated with MSAs, including the taxanes and epothilones, possibly because microtubule stabilization may damage cells within peripheral nerves.
Firstly, PDT may damage cells directly causing apoptosis and/or necrosis (Luo and Kessel, 1997); secondly, PDT may cause blood flow stasis by vessel constriction, platelet aggregation and/or fibrin plugging.
These observations and our findings suggest that Big Dyn and Dyn A, which concentrations are high at the sites of their release may damage cells by acting through noncanonical, non-opioid mechanism.
In the present investigation, concentrations of protein and non-protein sulfhydryl groups as well as activities of the antioxidant enzymes such as SOD and CAT were severely reduced in the colon following AA administration, which clearly indicates increased level of oxidative stress which may damage cells by lipid peroxidation of membranes and oxidation of cellular proteins.
